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AVENUE Q The Musical – an unholy alliance of humans and puppets – opens at QPAC on Saturday, February 20.

Directed by Jonathan Biggins and featuring a stellar cast including Mitchell Butel, Natalie Alexopoulos, David James, Luke Joslin, Christina O'Neill, Frank Hansen, Leah Howard, Josie Lane and Gus Murray, Avenue Q comes to Brisbane after delighting audiences in Melbourne, Sydney, Canberra, Adelaide and Perth.

Avenue Q is not the most upmarket of New York streets, and is about as far away from Park Avenue as you can get, but it is home to some lively and off-the-wall characters.

Princeton, a bright-eyed college graduate, has just moved to the neighbourhood as he desperately tries to follow his dreams and discover his ever-elusive purpose in life.

A tine bank balance, the distraction of a busty blonde and a variety of weird and wonderful friends and neighbours lead Princeton on a hilarious story of self-discovery.

Life may suck on Avenue Q but being jobless, homeless, politically incorrect, having sex (whether hetero, homo or porno … and that's just the puppets) are some of the topics featured in the terrific songs of this show.

For those weaned on Sesame Street, the Avenue Q puppets may look familiar, but with musical numbers like Everyone's A Little Bit Racist and If You Were Gay, this send-up of political correctness isn't for the kiddies.

Avenue Q caused a sensation at the 2004 Tony Awards by beating blockbuster Wicked to win the three most coveted awards: best musical, best book and best score. The production is still playing on Broadway to packed houses six years later.

Brisbane audiences will have the opportunity to see what all the fuzz is about when this award-winning musical comes to QPAC from February 20.

Tickets: Tuesday – Friday, Saturday matinee and Sunday $54.90; Saturday evening $64.90; previews $54.90/$44.90; concession tickets are $44.90 (not Saturday evening); previews $34.90. Tickets are available through QTIX on 136 246 or at the website.